E2 Supplement for Breast Cancer Xenograft
For estrogen-dependent breast cancer models, such as MCF-7, it is necessary not only to inoculate cells in the mouse mammary gland but also to provide additional estrogen to promote tumor growth.
Key Advantages
- ✓ Successfully used for various estrogen-dependent breast cancer xenografts (MCF-7, ZR-75-1, BT474, T47D and breast cancer PDXs)
- ✓ Stable and controlled release lowering estrogen crystal formation in bladder
- ✓ No or less manual urination assistance required
Product Information
| Product | 17β-estradiol | Cat# | Release | Units/Pack | Price (USD) |
|---|---|---|---|---|---|
| E2 supplement implant-60D | 0.36 mg | XLME-60-B | 60 days | 20 | $855 |
| E2 supplement implant-90D | 0.54 mg | XLME-90-B | 90 days | 20 | $860 |
Case Studies
MCF-7 Xenografts Study
Download ProtocolStudy conducted with E2 supplement implant-60D (XLME-60-B) on NOD-SCID mice, demonstrating efficacy with fulvestrant treatment.
BT474 Xenografts Study
Download ProtocolStudy using E2 supplement implant-90D (XLME-90-B) on NOD-SCID mice, showing consistent results over 90 days.
Implementation Guide
Watch our detailed video guide on implant placement